Accuracy of Stroke Diagnosis Using FAST (Face, Arm, Speech, Time) Tool by Emergency Medical Service Dispatchers and Technicians and its Impact on Transport Time


Peyman Saberian ORCID 1 , 2 , Nader Tavakoli ORCID 3 , Parisa Hasani-Sharamin ORCID 4 , Mehrad Aghili ORCID 1 , 5 , Alireza Baratloo ORCID 1 , *

1 Prehospital and Hospital Emergency Research Center, Tehran University of Medical Sciences, Tehran, Iran

2 Anesthesiology Department, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

3 Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran

4 Tehran Emergency Medical Service Center, Tehran, Iran

5 Department of Emergency Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

How to Cite: Saberian P , Tavakoli N , Hasani-Sharamin P , Aghili M , Baratloo A. Accuracy of Stroke Diagnosis Using FAST (Face, Arm, Speech, Time) Tool by Emergency Medical Service Dispatchers and Technicians and its Impact on Transport Time, Arch Neurosci. Online ahead of Print ; In Press(In Press):e98691. doi: 10.5812/ans.98691.


Archives of Neuroscience: In Press (In Press); e98691
Published Online: December 18, 2019
Article Type: Research Article
Received: October 7, 2019
Revised: November 16, 2019
Accepted: November 27, 2019
Uncorrected Proof scheduled for 7 (1)

Objectives: This study aimed to determine the accuracy of the Face-Arm-Speech-Time (FAST) screening tool used by emergency medical dispatchers (EMDs) and emergency medical technicians (EMTs) for the diagnosis of acute stroke and its effect on the patient’s transfer time from the scene to the hospital.

Methods: This study was conducted retrospectively during a one-year period. Via census sampling, we recruited all patients over 18-years-old diagnosed with acute stroke whether by EMDs or by EMTs. Pre-hospital operation forms and hospital records were used for data gathering. Final diagnoses were finally determined according to the patients’ brain magnetic resonance imaging (MRI).

Results: Totally, 1,280 patients with a mean age of 64.1 ± 17.8 years were studied, of whom, 730 were men (57%). Accordingly, 1,016 probable cases of stroke (79.4%) were reported by EMDs, while only 543 cases (42.4%) were reported as suspected cases of stroke by EMTs at the scene of the incident. Ultimately, stroke was confirmed in 519 (40.5%) cases. Accordingly, the Area under the curves (AUCs) for EMDs and EMTs were 0.50 (0.48 to 0.53) and 0.74 (0.71 to 0.76), respectively. Transport time (TT) was shorter if the initial diagnosis of stroke was made by EMTs. The TT was marginally significant and patients with stroke diagnoses were transported to the hospital faster than others (17.3 ± 11.5 vs. 18.5 ± 11.9 min; P = 0.065).

Conclusions: The use of FAST by EMTs for detecting probable acute stroke has acceptable sensitivity and specificity; but when it is used by EMDs, it has higher sensitivity and very low specificity. The diagnosis of stroke by EMTs may lead to faster transport to the hospital.


Early Diagnosis Emergency Medical Services Patient Transfer Stroke

Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

1. Background

Stroke is a major cause of death and disability in the working-age population (1). Eight of every 10 stroke patients are of the ischemic type, which is caused by the obstruction of a cerebral artery. In these cases, the blocked vessel can be opened by thrombolytic therapy or thrombectomy within a few hours of the onset of symptoms (2, 3). However, a few patients receive such treatments, which is mainly due to the delay in arriving at a hospital (4, 5). Emergency medical service (EMS) can play a vital role in this regard. It must quickly identify patients who are still within the golden time of recanalization treatments and transfer them to a hospital equipped with sufficient diagnostic and therapeutic capability (4, 6). The EMS personnel are usually the first professional people who deal with an acute stroke patient. The delay in the transfer of the patient to the hospital can be significantly reduced through the improvement of EMS personnel performance in this area (7).

The patients’ screening tool used by EMS is one of the effective factors in improving performance. Stroke detection in the pre-hospital phase has remarkably improved since the establishment of specific pre-hospital scales such as the Cincinnati Pre-Hospital Stroke scale (CPSS), Face-Arm-Speech-Time (FAST), and Los Angeles Pre-Hospital Stroke screen (LAPSS) (8, 9). The FAST and CPSS tools contain only three clinical items while LAPSS is more detailed and has a separate section for history taking and clinical examination. However, the overall efficiency of these three scales has been similar in comparative studies. Systematic review studies have not identified a superior diagnostic tool yet. However, many of the studies are criticized for their methodological errors, small sample size, and differences in incidence, prevalence, and pre-hospital operations (10). In spite of all these, FAST is one of the best tools in the pre-hospital screening of patients suspected of acute stroke (11, 12).

Since July 22, 2016, Iran has launched the system of “724” (providing specialized services for acute stroke patients 7 days a week/24 hours a day) in some hospitals and the activation code of SAMA (emergency stroke) using the FAST screening tool in pre-hospital centers. Its aim is to rapidly diagnose and screen patients suspected of acute stroke and to create more coordination between the pre-hospital system and acute myocardial infarction centers for faster transport of stroke patients (via air and ground transport) into centers with thrombolytic therapy facilities.

There has not been a comprehensive study on the accuracy of this tool in a real situation in Iran after running FAST for acute stroke screening.

2. Objectives

Thus, this study aimed to determine the accuracy of the FAST screening tool used by emergency medical dispatchers (EMDs) and emergency medical technicians (EMTs) for the diagnosis of acute stroke and its effect on the patient's transfer time from the scene to the hospital.

3. Methods

3.1. Study Design

This diagnostic accuracy study was conducted retrospectively based on a data registry. In this study, the patients’ data were collected during a one-year period from September 23, 2017, to September 23, 2018.

3.2. Definition

After calling 115, according to the existing algorithm and the tool of FAST, the EMDs start targeted interviews with the caller and then the nearest definite center will be announced. Emergency medical technicians (EMTs) immediately activate the SAMA code following the diagnosis of positive FAST symptoms. The necessary vital signs are taken and the transport of the patient will be announced to the definite hospital through the dispatch center. Patients with stable hemodynamics are sent to the computed tomography (CT) scan unit while patients with unstable conditions are sent to the emergency department (ED) and the treatment process will continue at the hospital.

3.3. Study population

Via census sampling, we included all patients over 18-years-old with suspected acute stroke based on the initial diagnosis made by EMDs, followed by EMTs. The selected patients had no history of trauma and had been transferred by the EMS personnel to three hospitals affiliated to the Iran University of Medical Sciences. The patients were excluded if their records were incomplete or the patient died before the arrival of paramedics. Based on previous studies (Williams et al. (13), Mould-Millman et al. (14)) and assuming a 50% sensitivity of the FAST tool in diagnosing acute stroke, a prevalence of 54% of stroke in suspected patients, accuracy of 95%, and a 5% error in sensitivity estimation, the minimum sample size required for this study was 710 cases.

3.4. Data Gathering

For this purpose, we used EMS operation forms and hospital records in a one-year period as registered in the hospital 724 databases (acute stroke treatment management services). The cases of acute stroke were finally determined at the hospital according to the patients’ brain magnetic resonance imaging (MRI). Three time-intervals were considered including response time (RT) defined as the call time to the time of arrival at the scene, scene time (ST) defined as the time of arrival at the scene to the time of scene departure, and transport time (TT) defined as the time of scene departure to the time of arrival at the hospital. The time intervals were obtained from GPS data recorded in the registry of the Tehran EMS center and information recorded in the patient’s pre-hospital file.

3.5. Statistical Analysis

Descriptive data were presented as mean ± standard deviation (SD) for quantitative variables and were summarized by absolute frequencies and percentages for categorical variables. Accuracy of a stroke diagnosis by EMDs and EMTs was assessed by the area under the ROC curve (AUC). Besides, we calculated sensitivity and specificity with 95% confidence intervals (CIs) for stroke diagnosis by EMDs and EMTs compared to the final diagnosis made at the hospital as the gold standard. Positive predictive value (PPV) and negative predictive value (NPV) with 95% CIs were calculated based on gold standard prevalence.

We used the independent t-test for assessing the effect of a stroke diagnosis by EMDs and EMTs on the mean of pre-hospital time. A P value of < 0.05 was considered statistically significant. All statistical analyses were performed using SPSS version 22.0 software (Armonk, NY: IBM Corp) and STATA version 14 (Stata Corp LLC).

4. Results

Totally, 1,280 patients were studied with a mean age of 64.1 ± 17.8 years. Of these, 730 were men (57%) and 550 (43%) were women. The mean age was 63.69 ± 17.8 and 64.65 ± 17.9 in men and women, respectively. Ultimately, stroke was confirmed in 519 (40.5%) cases. The basic information of patients is summarized in Table 1. Accordingly, 1,016 probable cases of stroke (79.4%) were reported by EMDs while only 543 (42.4%) cases were reported as suspected cases of stroke by EMTs at the scene of the incident. Among the symptoms reported by the EMTs, weakness (37.3%), sensory and motor disorder (16%), and headache and dizziness (11.7%) were the most frequent ones, in sequence. Regarding the history of diseases, 72 (5.6%) cases reported a positive history of stroke and 1168 (91.3%) had other chronic diseases such as diabetes, hypertension, heart disease, and cancer while only 40 (3.1%) did not report any specific disease history.

Table 1. Basic Information of Studied Patientsa
Male730 (57.0)
Female550 (43.0)
Presenting symptoms
Weakness478 (37.3)
Sensory and motor disorder250 (16.0)
Headache and dizziness150 (11.7)
Loss of consciousness106 (8.3)
Dyspnea88 (6.9)
Nausea and vomiting67 (5.2)
Chest pain33 (2.6)
Fever and shivering21 (1.6)
Other132 (10.3)
Past medical history
Stroke72 (5.6)
Other diseases1168 (91.3)
None40 (3.1)
EMD’s initial diagnosis of stroke
Yes1016 (79.4)
No264 (20.6)
EMT’s initial diagnosis of stroke
Yes543 (42.4)
No737 (57.6)
Final diagnosis of stroke
Yes519 (40.5)
No761 (59.5)

Abbreviations: EMD, emergency medical dispatcher; EMT: emergency medical technician.

aValues are expressed as No. (%).

Table 2 shows cross-tabulation for the diagnosis of stroke by EMDs and EMTs based on the standard diagnosis (acute stroke detection at the hospital). Accordingly, the AUC was 0.50 (0.48 to 0.53) for the EMD group, with sensitivity and specificity of 80.0% and 21.0%, respectively. The AUC was 0.74 (0.71 to 0.76) for the EMT group, with sensitivity and specificity of 70.7% and 76.9%, respectively. The positive predictive value (PPV) and negative predictive value (NPV) were 40.8% and 60.6% for EMD diagnosis, respectively, while PPV and NPV were 67.5% and 79.4% for EMT diagnosis, respectively (Table 2).

Table 2. Frequency of Correct and Incorrect Initial Diagnoses of EMDs and EMTs Based on the Final Diagnosis Made at the Hospitals Along With Accuracy and Predictive Value
EMS PersonnelFASTStrokeSensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)
Rule-in (N = 519)Rule-out (N = 761)
DispatchersPositive41560180.0 (76.2, 83.3)21.0 (18.2, 24.1)40.8 (37.8, 43.9)60.6 (54.5, 66.6)
TechniciansPositive36717670.7 (66.6, 74.6)76.9 (73.7, 79.8)67.5 (63.4, 71.5)79.4 (76.3, 82.3)

Abbreviations: CI: confidence interval; EMD: emergency medical dispatcher; EMS, emergency medical service; EMT: emergency medical technician; FAST: Face-Arm-Speech-Time; NPV: negative predictive value; PPV: positive predictive value.

The RT was not significantly different in the report of EMDs based on having or not having a stroke [mean ± SD (min): 13.0 ± 0.2 vs. 12.9 ± 0.4; P = 0.750]. The ST and TT were the lowest for patients with stroke based on the initial diagnosis made by EMTs. Although ST was not significantly different [mean ± SD (min):16.0 ± 9.6 vs. 16.7 ± 10.0; P = 0.270], TT was marginally significantly different and patients with stroke diagnosis were faster transported to the hospital [mean ± SD (min):17.3 ± 11.5 vs. 18.5 ± 11.9; P = 0.065].

5. Discussion

According to the findings of this study, FAST had acceptable sensitivity to stroke detection, but its specificity, especially when used by EMDs, was very low. However, this flaw was partially resolved when the tool was used by EMTs in the scene. Besides, the results showed that stroke detection by EMDs did not have an effect on the reduction of any pre-hospital times. On the contrary, stroke detection by EMTs was associated with reduced transport time.

We observed that EMD’s sensitivity was more than that of EMTs (79.9% vs. 70.7%). On the other hand, EMT’s specificity to detect acute cerebral stroke was higher than that of EMDs (76.8% vs. 21.1%). It was expected that the sensitivity of the test in telephone calls and the use of the tool by EMDs were higher, subsequently, the EMTs, according to the requirements of this stage, in order to prevent healthy people from entering health care cycle, the test’s specificity was increased so that healthy people do not enter the process of treatment.

Comparing the FAST’s validity features with previous study findings, Zhao et al. (15) found that the sensitivity, specificity, and PPV of EMS personnel were 85.7%, 93.5%, and 80%, respectively, using FAST for the diagnosis of acute stroke in the pre-hospital emergency. Therefore, their study found more sensitivity and specificity than our study (15).

In the study by Caceres et al. (16), patients diagnosed with stroke by EMDs were transferred to the hospital significantly sooner than those not diagnosed with stroke by EMDs. In this study, we also expected that the speed of the patient’s transfer to the hospital varied based on the diagnosis of acute stroke or its absence; in other words, we expected that the diagnosis of acute stroke by EMD would lead EMS personnel to deploy faster and the patient was transferred to the hospital quicker. On the contrary, reviewing patients’ transport times showed that the EMD’s decision did not affect the patient’s transport time to the hospital. However, the patient’s transport time significantly reduced when EMTs detected the stroke.

5.1. Limitations

The FAST tool has some limitations in detecting an acute stroke. In the study by Aroor et al. (17), 104 out of 736 (14.1%) patients diagnosed with acute stroke did not have any symptoms of FAST. The BE-FAST test (B for Balance and E for Eye) could be used considering the fact that most of these patients had an imbalance and visual impairment. Thus, using BE-FAST, 4.4% of patients did not have BE-FAST symptoms (17). Therefore, we can add more symptoms to FAST, but it requires staff training and increases the number of healthy people who receive health care. In addition, in a study by Pickham et al. (18), adding balance and double vision to FAST did not increase the diagnosis of stroke in the pre-hospital emergency. However, further studies are required in this field considering the discrepancy of the results of research.

5.2. Conclusions

The use of FAST by EMTs in detecting acute stroke has an acceptable sensitivity and specificity and it can be used as a screening tool for acute stroke in pre-hospital emergency settings (Figure 1). Accuracy indices in the diagnosis of stroke by EMDs showed that sensitivity was very higher than specificity that is a feature of diagnostic tests/measures in low levels in which by placing high sensitivity, we try to miss the minimum number of patients and reduce false-negative cases. On the other hand, the low specificity of this tool when used by EMDs caused over-triage, which may lead to diminishing the EMT’s sensitivity to SAMA noticed by the dispatch center; thus, the response time did not significantly differ. This issue requires attention and training. The validity indices in the diagnosis of stroke by EMTs show that the specificity of the test has increased at this stage so that healthy (non-stroke) people are well distinguished. To prevent the entry of healthy people into the care cycle, which increases the intervention and treatment costs, it is necessary to increase the specificity of tests/measures.

Medical illustration of the current study
Figure 1. Medical illustration of the current study




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